Search on: BOWEN'S DISEASE 
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Descriptor English:   Bowen's Disease 
Descriptor Spanish:   Enfermedad de Bowen 
Descriptor Portuguese:   Doença de Bowen 
Tree Number:   C04.557.470.200.400.130
C04.557.470.700.400.130
Definition English:   A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9) 
Indexing Annotation English:   /blood supply /chem /second /secret /ultrastruct permitted; coord IM with SKIN NEOPLASMS (IM)
History Note English:   91(75); was see under CARCINOMA, SQUAMOUS CELL 1981-90; was see under CARCINOMA, EPIDERMOID 1969-80 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   1938 
Unique Identifier:   D001913 

Occurrence in VHL:
 

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